HELICOBACTER PYLORI STRAINS FROM A NIGERIAN COHORT SHOW DIVERGENT ANTIBIOTIC RESISTANCE RATES AND A UNIFORM PATHOGENICITY PROFILE.

Helicobacter pylori strains from a Nigerian cohort show divergent antibiotic resistance rates and a uniform pathogenicity profile.

Antibiotic resistance in Helicobacter pylori is a factor preventing its successful eradication.Particularly in developing countries, resistance against commonly used antibiotics is widespread.Here, we present an epidemiological study from Nigeria with 111 isolates.We analyzed the associated disease outcome, and performed a detailed characterization

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RNA-Based Vaccines in Cancer Immunotherapy

RNA vaccines traditionally consist of messenger RNA synthesized by in vitro transcription using a bacteriophage RNA polymerase and template DNA that encodes the antigen(s) of interest.Once administered and internalized by host cells, the mRNA transcripts are translated directly in the cytoplasm and then the resulting antigens are presented to antig

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